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Studies confirm 50% drops by midlife, linking to aging symptoms.[1][9] Restoring NAD+ has been shown in animal studies to improve lifespan and healthspan, with human trials indicating benefits in muscle function and cognitive performance

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The frequency distribution of AEs was similar in both treatment groups: for ARA 290, 54 mild, 9 moderate and 1 severe categorizations were recorded, while for placebo, 61 mild and 5 moderate were noted