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TABLE 2 A summary of different types of nanoparticles, the loaded cargo, particle size, and advantages of drug encapsulation in melsma management

Especially, the detailed knowledge of the nanocarrier-transporter complex internalization and following sorting processes and exocytosis would enable rational design of nanocarriers capable of efficient transcytosis across the BBB by minimizing the lysosomal degradation of the nanocarrier in the endothelial cells

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Bielmann A, Sambiagio N, Wehr N, Gerber-Lemaire S, Bochet CG, Curty C