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Description Why 5-Amino-1MQ Is Redefining Lipid Metabolism Research Selective NNMT inhibitor -35% fat mass in 11 days without appetite reduction (preclinical model) Enzymatic Target NNMT Inhibitor Selective inhibition of nicotinamide N-methyltransferase (IC50 = 1.2 M)

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Science 313 , 314318 (2006)

The invasion index was used to assess cancer cell migration and invasion (invasion index = /), and the growth index was used to evaluate the ability of dorsal root ganglion axons to grow toward cancer cells (outgrowth index = /) (Supplementary Fig