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Green tea extract is naturally rich in antioxidants, which has a cell-protecting function as well

Taken together, these data show that although ABCC1 did not contribute to the acquired resistance to Venetoclax, inhibition of ABCC1 can restore Venetoclax sensitivity in resistant AML cells

2004a Apr 1;19(7):739-47

Inhibiting the system x/glutathione axis selectively targets cancers with mutant-p53 accumulation

Overproduction of reactive oxygen species (ROS) in the nucleus pulposus cells (NPCs) is a critical contributor to the progression of IDD through increasing oxidative stress in the microenvironment of the extracellular matrix (ECM) 5 , leading to ferroptosis and long-term persistent inflammation 6,7 , which would cause the loss of structure and function in the intervertebral disc (IVD) ultimately