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In addition to the enhanced antioxidative enzyme defense observed in dwarf mice, protein glutathionylation likely plays a role in these mice in protecting protein thiols from oxidative-induced damage [48]

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Thus, the restored GSH/GSSG balance under nanoparticle treatment suggests an enhanced recycling of oxidized glutathione and a more robust detoxification of peroxides, ultimately facilitating stress tolerance

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Marked species differences exist for ADHs including genes, proteins, enzymatic activity, and tissue distribution

Like in obese humans, this study also finds similar results where the proportion of Firmicutes and Bacteroidetes is associated with obesity[57]