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Synaptic economics: competition and cooperation in synaptic plasticity

23: 112636 Tang L, Persky AM, Hochhaus G, et al

Lysosomal cholesterol activates mTORC1 via an SLC38A9NiemannPick C1 signaling complex

However, megaloblastic anemia due to these drugs is rare

This randomised, double-blind, placebo-controlled trial enrolled 706 adults with overweight or obesity (BMI 27 or above) across multiple dose groups, running over 26 weeks