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To further investigate how ferroptosis could affect glia cells in AD, we looked at the difference in expression of ferroptosis-related genes in microglia between control and AD brains containing only amyloid- plaques in the occipital cortex (OC) and both amyloid- and tau pathology in the occipitotemporal cortex (OTC) ( p -value below 0.05 was used to determine the significance (Table 2)

Saha JC, Dikshit AK, Bandyopadhyay M, Saha KC

While most of the ORFs on the three contigs were not assigned a metabolic annotation (Figure 3

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Vainchtein ID, Molofsky AV

Therefore, timing, dosage, and purpose of glutathione administration are critical