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There is also a lack of co-stimulatory molecules such as CD40, CD40L, CD80, CD86 in MSCs which make them evading of T cell recognition [26,27,28,29]

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Lipoprotein(a) as a Risk Factor for Venous Thromboembolism: A Systematic Review and Meta-analysis of the Literature

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However, most of these signaling pathways are either redundant or essential in healthy tissue making these types of target therapies challenging