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Catalyst-free decarboxylation of carboxylic acids and deoxygenation of alcohols by electro-induced radical formation

Gwinn D, Shackelford D, Egan D, Mihaylova M, Mery A, Vasquez D, et al

Antioxidants 14 , 297 (2025)

In a single-center, randomized, double-blind, placebo-controlled trial conducted at the Emergency Department of a hospital in Brazil, 140 patients with severe COVID-19 infection and oxyhemoglobin saturation of less than 94% or respiratory rate higher than 24 breaths/minute were randomized to receive N-acetylcysteine 21,000 mg (approximately 300 mg/kg) for 20 hours or dextrose 5% (placebo)

and 2018YFA0507802 to F.W.)