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DNA Repair 68 , 2533 (2018)

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Annu Rev Biochem 74:791831

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Mechanistically, microbial dysbiosis exacerbates renal injury and fibrosis by increasing intestinal permeability, disrupting lipid metabolism, inducing ROS-mediated oxidative stress, and activating TLR4-mediated inflammatory responses ( Figure 4 ) [128]

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