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The visibility of the discoloration in people with darker skin can also amplify stigma and emotional distress

In ME/CFS patients, the scarcity of butyrate-producing bacteria could be due to low levels of SCFA, potentially causing post-exertional malaise and a cycle of inactivity

Gastrointestinal effects are the most common and include nausea, vomiting, diarrhea, and constipation

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What matters most is thoughtful assessment and individualized planning

Fatigue Some researchers report fatigue during the first few weeks, particularly at the 0.25 mg and 0.5 mg stages