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Acrylamide is a carcinogen

Within the pathological milieu of uremia-associated CKD, the intestinal microbiome undergoes profound compositional dysregulation, manifesting as precipitous depletion of beneficial microbial taxaparticularly short-chain fatty acid (SCFA)-producing genera including Faecalibacterium prausnitzii , Roseburia, Bifidobacterium, and Lactobacillusconcomitant with the aberrant proliferation of opportunistic pathogenic species such as Escherichia coli , Shigella, and Enterococcus (Lyu et al., 2023

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doi: 10.1038/labinvest.2012.13 118 LindforsKBlomqvistTJuuti-UusitaloKStenmanSVenlinenJMkiMet al

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