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Importantly, the neuroprotective effects of Immunocal observed in cell culture are dependent on the de novo synthesis of GSH (Winter et al., 2017)

35,36 In one study, the catabolism and uptake of collagen fragments were found to support PDAC tumour survival, by using macropinocytosis amongst other mechanisms when nutrient-deprived

(Reference Falck-Ytter, Guyatt, Vist and Kunz20) Statistical analysis The mean changes and standard deviations (SDs) of the outcome of interest for the intervention and placebo groups were used to estimate the effect sizes

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