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Ethics declarations Competing Interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

K.BoukhedimiY.McAlonis-DownesM.LobsigerC

We demonstrated that this occurred through increased hexokinase activity and elevated pyruvate contents in the renal tissue of injured mice

a rate-limiting enzyme of GSH synthesis) and GSS

60 KondrashovF

134 However, because of heterogeneity among cancer cells, other studies have shown that IDH2 expression is decreased in metastatic HCC and gastric cancer tissues compared with paired normal tissues