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While all patients complained of moderate-to-severe pain before treatment, 42% of patients in the treatment group were pain-free two weeks after taking the combination therapy versus only one patient in the placebo group

A., Godowski, P

Moreover, MDD has been linked to characteristics commonly associated with aging, suggesting that it may contribute to a premature aging phenotype, particularly in older adults who are already at heightened risk [489, 495]

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Activation of the classical complement pathway is initiated by C1qs recognition of specific molecules on the surface of apoptotic or stressed cells, such as calreticulin, which serves as a canonical eat-me signal that facilitates C1q binding (115)

Brando et al., 1999), respectively