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In HCC, the proline biosynthetic enzymes P5CS and PYCR1 are markedly upregulated [276, 277]

Br J Haematol 60(4):677-86, 1985

Consulta con un profesional para valorar el origen y el enfoque adecuado

[PubMed] [Google Scholar] 81.Cantarel B.L., Waubant E., Chehoud C., Kuczynski J., Desantis T.Z., Warrington J., Venkatesan A., Fraser C.M., Mowry E.M

Additionally, lipid peroxidation has been noted in cardiovascular complications related to COVID-19 and in the heart pacemakers of SARS-CoV-2-infected hamster models [85, 86]

It is therefore assumed that transcription from gdhA P2 serves to enhance gdhA expression when the concentration of -ketoglutarate is low, as during invasive disease, both to enhance the activity of the TCA cycle in the catabolic reaction, and to provide L-glutamate for glutathione biosynthesis in the anabolic reaction