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Dhanvantari S, Shen FS, Adams T, Snell CR, Zhang C, Mackin RB, Morris SJ, Loh YP (2003) Disruption of a receptor-mediated mechanism for intracellular sorting of proinsulin in familial hyperproinsulinemia

GLP-1RAs Acting Through the Gut-brain-lung Axis GLP-1R activation attenuates systemic inflammation and TNF- production, induced by multiple Toll-like receptor agonists, through the gut-brain axis, specifically via the central neuronal GLP-1Rs

Laboratory investigations using ionizing radiation-induced senescent cells demonstrate that FOXO4-DRI causes p53 nuclear exclusion and mitochondrial targeting, validating the proposed mechanism of selective senescent cell elimination through targeted protein-protein interaction disruption