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HGF/c-MET signaling The complex phenotype that results from c-MET signaling involves a number of molecular events, which have been described in detail in previous reviews [Trusolino et al

Given the fact that cancer patients were only treated with vitamin C orally in the Mayo Clinic studies, the studies do not disprove high dose vitamin Cs efficacy as a cancer treatment

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In the context of mitohormesis, growing evidence suggests that an evolutionary hunter-gatherer dietary lifestyle aimed at balancing (1) minimally-processed, carbohydrate-restricted feeding periods (challenging, not excessive, stressor phases) with (2) intermittent fasting protocols (complete, not excessive, recovery phases) should be considered as a preventative and therapeutic strategy for neurodegenerative disorders

Yacoubian TA, Standaert DG