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The present paper aims to conduct a review of available data on the effect of soy, soy foods and soy components on women's fertility and related outcomes

10.1093/jnen/nly024 151 SensiS

NAD+ helps maintain brain health by supporting mitochondrial function in brain cells and protecting against neurodegenerative diseases

Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

The method was also applied to whole blood for a more accurate tabulation of tissue blood content

Short answer: We simply dont know long-term