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Although Htr3a KO mice showed reduced weight gain in HFD-induced obesity model, their WAT did not show remarkable differences in fat mass and histology compared with WAT of WT littermates (Figs 7a,b and 8e), suggesting that insulin resistance of Htr3a -null WAT was comparable to WT WAT

Despite the initial belief that NEOs have low mammalian toxicity, there is growing evidence that NEOs can cause a wide range of toxic effects in animals and humans, including neurotoxicity, immunotoxicity, hepatotoxicity, nephrotoxicity, and reproductive cytotoxicity in vertebrates and invertebrates (Wang et al

Thus, it is possible that the coordination of androgen-mediated action in these cell types through AR-dependent or -independent action may contribute to overall changes in body composition

Fedt kan kun forbrndes i de mitokondrier, der er cellernes kraftvrker

To address these limitations, this study adopted a within-group pooling strategy

Pyruvate, -ketoglutarate, glutamate, and aspartate all stayed constant between the two groups (Figure 1)