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In addition, it should be taken into account that TCEP itself can suffer some decomposition in phosphate buffers at neutral pH ( AX Transformation Into DKP Implies a Loss of Reactivity and Antibacterial Potency DKP is a known metabolite of AX, considered to have lower or residual reactivity and bacteriostatic activity ( 1 H-NMR analysis of incubation mixtures containing equimolar amounts of DKP and butylamine revealed quantitative preservation of DKP (95% of the starting amount), thus confirming its lack of reactivity

In this process, free radicals steal electrons from lipids in the cell membrane, thereby leading to cell damage

March 10, 2025

As a final immune effector, NO generated by inducible NO synthase, kills pathogens and abnormal cells but may play a detrimental role by damaging normal host tissue and cells, especially when inducible NO synthase is persistently expressed [20]

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