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PMID 25928094

An algorithm for treating TNF alpha inhibitor psoriasiform eruptions has been proposed and is based on severity of skin eruption and control of the underlying disease:11 Findings are mixed on whether TNF alpha inhibitors increase the risk of nonmelanoma skin cancer.14 In a meta-analysis of four observational studies with 28,000 patients, the risk of non-melanoma skin cancer was significantly higher among patients exposed to these drugs.14 However, the data are confounded by past or concomitant use of phototherapy or other immunosuppressive agents

Secondary analyses of these studies suggested that weight loss might be the main driver of GLP-1RA efficacy in MASH, supported by the lack of expression of GLP-1 receptors in the human liver 93