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For example, eicosanoids can play an important role in tumorigenesis by regulating apoptosis and proliferation of cancer cells ( Reference Sheng, Shao and Morrow 83 , Reference Avis, Hong and Martnez 84 ) and Se may exert anti-cancerous properties through the manipulation of eicosanoid signalling

Commonly used indicators of ROS alteration in intact muscle fibers, such as fluorescent probes and spin traps, have limited specificity to the types of ROS (Powers and Jackson, 2008

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