glutathione synthetase deficiency oxoproline Pyroglutamic acidosis A yeast model of 5-oxoproline
A yeast model of 5 oxoproline accumulation reveals a general toleration to 5 oxoproline bioRxiv 5 Oxoprolinuria as a Cause for Metabolic Acidosis Renal Fellow Network 5Oxoprolinase deficiency: report of the first human OPLAH mutation Almaghlouth 2012 Clinical Genetics Wiley Online Library Mutations in the glutathione synthetase gene cause 5oxoprolinuria Nature Genetics Recurrent High Anion Gap Metabolic Acidosis Secondary to 5 Oxoproline (Pyroglutamic Acid) American Journal of Kidney Diseases Full article: The acetaminophen metabolite N acetyl p benzoquinone imine (NAPQI) inhibits glutathione synthetase in vitro; a clue to the mechanism of 5 oxoprolinuric acidosis?
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