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In human colon cancer cell lines, HCT116 and SW480, sulforaphane diminished cell growth in a dose-dependent way, and increased apoptosis induced by Lactobacillus through the TNF pathway (Yasuda et al., 2019)

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After library preparation and quality control, double-end sequencing was performed on the Illumina Nova Seq6000 sequencing platform in 2 150 bp mode

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doi: 10.1074/JBC.M116.748632 145

The trial did not meet its efficacy endpoint, but tolerability was not the reason the program was discontinued