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The findings were notable for the effective doses (low milligram per kilogram in rats), the oral route of administration (most peptides require injection), and the magnitude of cognitive rescue

The preprint did not indicate whether these findings were statistically significant

Additionally, rapid injection speed pushes the medication into tissue faster, increasing pressure and nerve stimulation

Ann Intern Med 1995;123:280-287

Regardless of the limited success shown in these two studies, further investigations with more subjects and optimized doses to observe more significant improvements in patients are necessary to conduct

Nouri A, Ghatreh-Samani K, Amini-Khoei H, Mohammadi A, Heidarian E, Najafi M (2022) Ferulic acid prevents cyclosporine-induced nephrotoxicity in rats through exerting anti-oxidant and anti-inflammatory effects via activation of Nrf2/HO-1 signaling and suppression of NF-kappaB/TNF-alpha axis