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Human data are still limited, and long-term safety is unknown

Proceedings of the Royal Society of London 77(519):405-420. [doi.org]

Springer, Berlin, pp 167184 Urruticoechea A, Alemany R, Balart J, Villanueva A, Vinals F, Capella G (2010) Recent advances in cancer therapy: an overview

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The fact that the IOM did not establish an upper level (UL) at the time, since, as the institute stated, it cannot be determined due to a lack of data on adverse effects, does not mean that there are none