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Side effects from B12 injections are generally mild and can include pain at the injection site, mild diarrhoea, or a feeling of bloating

In a mouse model of heart ischemiareperfusion, ALT-2074 was shown to have a protective effect (Blum et al

JAMA 301(3):286294 Tyni-Lenne R et al (1999) Aerobic training involving a minor muscle mass shows greater efficiency than training involving a major muscle mass in chronic heart failure patients

doi: 10.1016/j.tim.2023.03.018 53

Kang SH (2013) Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

Pantethine offers a highly specific, mechanistic intervention for the mitochondrial dysfunction seen in complex chronic illnesses