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Rabbit immunizations In a first immunization study, 18 rabbits (New Zealand White, female, 3 groups, 6 animals/group) were immunized under subcontract at Covance (Denver, USA) with either 10 g AMS0232 E2 monomer, 22 g AMS0232 E2E1-I53-50A or 27 g AMS0232 E2E1-NP (equimolar to E2)