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While the RNA lantern design shows conceptual promise, critical challenges remain in optimizing mRNA stability and relaxing the stringent binding site requirements (Fig

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In mesenchymal TNBC which is a subcategory of TNBC and is featured with high rates of invasion and metastasis according to Lehmann BD work [57, 114], stable deletion of CD44 with shRNA vectors restrained proliferation, colony formation and invasion of SUM159, MDA-MB-436 and MDA-MB-231 [115]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 383.Schranz D., Voelkel N.F