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Interestingly, animal model studies employing dietary choline or TMAO, germ-free mice and microbial transplantation confirmed a role for gut microbiota-dependent TMAO production in modulating platelet hyperresponsiveness and thrombotic potential (78)

Journal of Exercise Nutrition & Biochemistry

Nascimento et al., 2021

De manera especfica, la colina es el precursor de la betana, que proporciona un grupo metilo para la conversin de homocistena en metionina a travs de la enzima, betana-homocistena metiltransferasa (BHMT)