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Univariate analysis incorporating fold change, t -test, and variable importance in projection (VIP) filtering revealed that, compared to the NC group, the DSS group exhibited significant changes in 57 metabolites in positive ion mode (26 upregulated, 31 downregulated

albicans and Cryptococcus neoformans , by constitutively protecting against oxidation, thereby boosting their pathogenic potential (Pais et al., 2016)

In terms of glutamate clearance, ceftriaxone effectively increases GLT expression in glial cells and enhances glutamate clearance (Lai et al., 2011)

doi: 10.1002/prot.25681

This aspect of its mechanism may influence its overall physiological effects and side-effect profile [10]

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