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The KD causes a state of physiological ketosis, altering brain energy metabolism from glucose to ketone bodies like -hydroxybutyrate and acetoacetate (Rusek et al., 2019

Ferrous iron predominantly contributes to the cellular labile iron pool (LIP), participating in key metabolic reactions but also toxic reactions that can lead to oxidative stress and eventually cell death

Compared with vehicle injection, retinal BF measured with MBR was reduced by 13% for 20 min after ET-1 injection (Fig 1A and B)

PLoS ONE 12 , e0178063 (2017)

Curcumin reduces neuroinflammation and suppresses beta-amyloid plaque formation in the brain

It is normally obtained from an animal-based diet (Wolffenbuttel et al., 2024)