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10.1186/s13578-019-0362-3 194 van der HeijdenC

Since 5-OP has been reported to cause oxidative stress and one of the stress response factors Skn7p was upregulated we examined this in greater detail

[DOI] [PMC free article] [PubMed] [Google Scholar] Hussein H.M., Al-Khoury D.K., Abdelnoor A.M., Rahal E.A

Our previous studies also demonstrated that knockdown or inhibition of IDO1 rescued the inflammation induced downregulation of SR-BI and cholesterol uptakes in macrophages, suggesting crucial roles of IDO1-KYN signaling the SR-BI regulation and cholesterol homeostasis

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Mechanisms of Action for Different Checkpoint Inhibitors