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Single-cell RNA sequencing studies in murine smoke models have identified an excessive influx of monocyte-derived macrophage subset population responsible for heightened inflammation and ECM remodeling, a finding that has also been validated in emphysematous COPD patients 59

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Aliment Pharmacol Ther 54:3242 Tommasi S, Yoon JI, Besaratinia A (2020) Secondhand smoke induces liver steatosis through deregulation of genes involved in hepatic lipid metabolism

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