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The three test articles compared in this study: a 3R4F reference Download Scientific Diagram HeatNotBurn Tobacco Aerosols Induce Immune Dysregulation and Barrier Disruption Comparable to Conventional Cigarettes Karaguzel 2026 Allergy Wiley Online Library Hybrid device delivers tobacco flavors with e cig like vapor EurekAlert! Assessment of toxicological validity using tobacco emission condensates: A comparative analysis of emissions and condensates from 3R4F reference cigarettes and heated tobacco products ScienceDirect CTRP The genotoxicological assessment of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay ScienceDirect
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