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Accumulating evidence further demonstrates that in pSS models, reduced gut microbiome diversity and diminished production of microbiota-derived metabolites lead to decreased tolerogenic dendritic cells (DCs) and Th17/Treg imbalance, consequently promoting autoantibody accumulation and exacerbation of glandular inflammatory responses in pSS (203)

Results: We included 102 patients

reduced their risk of disease progression by 54% compared to those taking fulvestrant and placebo

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GLP-1 receptor agonists like semaglutide and liraglutide improve glycemic control and reduce HbA1c levels in patients with type 2 diabetes

Occasional mild headache in the first few days of a new protocol usually temporary