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This review provides a detailed overview of recent investigations into the roles of IL-1 family cytokines in RA pathogenesis and critically examines the current status of drugs targeting these cytokines in clinical trials, thereby offering novel perspectives on the treatment of rheumatoid diseases

Moreover, there are several paradigmatic conditions such as Down syndrome, phenylketonuria, and various lipidoses (Scriver et al., 1989) where the metabolic abnormalities are expressed in both neural and peripheral tissues, but the functional consequences are most profound in the central nervous system (CNS)

A high GSH redox ratio was maintained because the GSH treatment increased the GSH content and decreased the GSSG content, compared with that in the As-treated seedlings ( Figures 4B, D, F )

Stem cell therapies for acute spinal cord injury in humans: a review

Additionally, curcumin has been shown to induce collagenase activity, which may help break down existing collagen bundles