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In addition, combinations with immune checkpoint inhibitors are being investigated as a strategy to reshape the tumor immune microenvironment and enhance anti-tumor immunity

Lipoic acid is a compound involved in aerobic metabolism

In glutamine-addicted squamous cell carcinoma (SCC) cancer cells, V-9302 treatment inhibits the YAP1/TEAD signaling pathway to weaken the SCC cancer phenotype (Mickle, 2022)