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Yan S, Jiao X, Zou H, Li K

Search Immunoprecipitation (IP) is a cellular and molecular biology method used in laboratories to isolate or purify a specific antigen (or protein of interest) via a solid phase (agarose or Sepharose resin or magnetic particles)

In good agreement with the above-described processes, carnitine seems to be involved also in insulin sensitivity (Figure 1): it was observed that the muscle accumulation of fatty acyl-CoA derivatives or acyl metabolites inhibits both insulin signaling and glucose oxidation (Pietrocola et al., 2015

Mechanistically, HK2 dissociation from the OMM promotes mitochondrial Ca 2+ uptake, VDAC oligomerisation and the release of mtDNA 219

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