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10.1016/S0076-6879(02)47039-5 86 MitraS

Single-atom Pd nanozyme for ferroptosis-boosted mild-temperature photothermal therapy

Specifically, the authors found that acute glycolytic inhibition increased glutathione and pyruvate metabolism

J.PhamS

The impact of changed redoxin function on ferroptosis could also be based on secondary effects, e.g., the increase in superoxide formation upon loss of mitochondrial redoxins [90,91] or activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway [92,93] , a major regulator of transcription of antioxidant and anti-ferroptotic enzymes [65]

The peptide's natural occurrence and enhanced bioavailability profile provide strong foundation for investigating novel therapeutic applications in muscle wasting disorders, neurodevelopmental conditions, and regenerative medicine