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On the other hand, elevated TBC1D15 expression to increase Rab7 hydrolysis reduced membrane contacts between LE/Lys and mitochondria to confer neuroprotective effects against neuronal injury induced by epileptic seizure [86]

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The second assessment performed by abstracts analysis, excluded studies in a language other than English, studies with lack of full text, reviews, case reports, animal studies and in-vitro studies

Finally, in future research, we plan to complement our findings with in vitro experiments and utilize gene editing technologies (such as CRISPR/Cas9) to regulate specific genes or construct transgenic mouse models, allowing for a more in-depth verification of the role of ferroptosis in the pathogenesis of BPH

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