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Cellular interaction and toxicity depend on physicochemical properties and surface modification of redox-active nanomaterials

Redox-fibrosis: Impact of TGF Beta 1 on ROS Generators, Mediators and Functional Consequences

10.1371/journal.pone.0009508 PLoS ONE 91 YaoJ

Nintedanib is a multikinase inhibitor targeting VEGF, platelet-derived growth factor (PDGF), and Fibroblast Growth Factor (FGF) receptors

This puzzling scenario of interpretations on the role of HO-1 clearly indicates that we still need to fully understand how to regulate its activity during the different phases of bacterial growth, into the different infectious contexts