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Human participants Serum zonulin levels were analyzed by ELISA (Cusabio Technology LLC, USA) and compared in cross-sectional manner in two cohorts: (i) 41 healthy female controls, 65 female predisease patients and 40 female RA patients from the Department of Internal Medicine 3 of the University of Erlangen-Nrnberg/Germany as well as (ii) 11 healthy female controls, 21 female predisease patients and 28 female RA patients from the Department of Rheumatology & Immunology of the West China Hospital in Chengdu/China

Dipy (v.1.5.0) [60] was applied over the corrected DWIs to fit both second order tensors and intravoxel orientation distribution functions (ODF) via the Simple Harmonic Oscillator-based Reconstruction and Estimation method (SHORE) [61]

Oral glutathione supplements typically show visible skin brightening effects after 812 weeks of consistent daily use

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*Correspondence: Helena C

These include: copy number loss of C-terminal Src homology 2 Adapter Protein 2 (SHC2) 9 , SNCA gene (synuclein alpha) single-nucleotide polymorphisms 10,11 and mutation in the CoQ2 gene which encodes for 4 hydroxbenzoate polyprenyltransferase (CoQ2), an enzyme involved in coenzyme Q10 (CoQ10) biosynthesis 12,13