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Methotrexate or valproic acid alone or in combination induced significant increase in tissue catalase and glutathione reductase with significant decrease in tumor volume, tissue malondialdehyde, cholesterol and tumor necrosis factor- and alleviated the histopathological changes with significant increase in p53 expression and apoptotic index compared to solid Ehrlich carcinoma group

Supplementary material The Supplementary Material for this article can be found online at: References 1 AdamsP

Additionally, the availability of samples from age-matched UFMs provided a cross-reference of the healthy state, even though BMI was not considered for the comparisons

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Clinical manifestations and stages of rett syndrome