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doi: 10.1080/17476348.2024.2397480 12

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Nature 511:319325

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Moreover, SLC7A11 and cyclin-dependent kinase inhibitor 1A (CDKN1A) gene expression is stimulated by the p53DPP4 interaction, thereby inhibiting ferroptosis (82)

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Impaired acidification, fusion defects and reduced endosomeautophagosomelysosome pathway flux compromise the clearance of pathogenic aggregates, and raising cellular cAMP or free zinc has been proposed as a strategy to restore lysosomal pH and proteolytic capacity in affected neurons 166

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Tab 2: CAR-T monoculture surfaceomes

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