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The anti-CD38 phycoerythrin (PE) and anti-CD138 fluorescein isothiocyanate (FITC) antibodies, and APO-DIRECT kit (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)) were purchased from BD Biosciences (San Jose, CA, USA)

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Additionally, it explores translational applications, including dietary interventions, probiotics, synbiotics, and fecal microbiota transplantation, emphasizing how microbiome-targeted strategies could modulate persistent symptoms and guide personalized therapy

These changes suggest a disruption in several metabolic pathways, including the biosynthesis of phosphatidylethanolamine, fatty acid synthesis, pyruvate metabolism, and mitochondrial acetyl group transfer, as indicated by pathway enrichment analysis

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