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doi: 10.1016/j.gene.2023.148055

Individuals with bleeding disorders or those taking blood-thinning medications should avoid using NAC, as it may slow blood clotting

Diabetes 54 , 29772982 (2005)

To measure total glutathione (GSH + GSSG), oxidized glutathione (GSSG) was reduced by incubating test samples with 500 M tris(2-carboxyethyl)phosphine (TCEP) for 10 minutes prior to luminescence measurement, following the manufacturer's instructions

Statements Author contributions XT: Conceptualization, Writing review and editing, Writing original draft

As we known lipid peroxidation produces MDA as one of its vital end-products, we found that Fer-1 treatment remarkably mitigated the MDA levels in the IGF2BP3-deficient + erastin groups (Fig