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Constitutive expression of mammalian nitric oxide synthase in tobacco plants triggers disease resistance to pathogens

This clearance mechanism has also been described in the context of different cellular stressors leading to PS exposure, e.g., hyperosmotic stress [217], plasmodium infection [77], oxidative stress [72], and, to some extent, also ageing of erythrocytes [218]

Menaker described PDE as a "piece of sensationalist fiction and tabloid journalism masquerading as a documentary" and an "exercise in media sensationalism"

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It is an issue that future research needs to address

Thats when oxidative stress builds up and starts causing damage at a deeper level