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Recent insights into the role of ChREBP in intestinal fructose absorption and metabolism

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Proline accumulation, a compatible solute Numerous studies have shown the accumulation of proline, a key compatible solute, plays a central role in stress tolerance [3], while antioxidant enzymes such as superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), and glutathione S-transferase (GST), together with antioxidants such as flavonoids and phenolics mitigate oxidative damage by neutralizing reactive oxygen species [6]

These variations are associated with alterations in epigenetic age, which depend on the clinical severity of the disease (Vonsattel et al., 1985)

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Glutathione in brain disorders and aging. Molecules 27.1 (2022): 324